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This study further denoted the importance of Apoe-Trem2 signaling pathway in connecting Apoe + mono-M and AMs

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Another mechanism through which it possibly achieves this is by inhibiting a growth-inhibiting factor, 4-hydroxynoneal, thereby allowing more growth and regeneration

At the same time, human milk oligosaccharides (HMOs) act as prebiotics and selectively promote a tolerable gut microbiome rich in beneficial bacteria such as Bifidobacterium and Lactobacillus, which are essential for training the immune system and maintaining a balance between inflammatory and regulatory responses [16, 17]